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Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex

Tight junctions (TJs) play a crucial role in the establishment of cell polarity and regulation of paracellular permeability in epithelia. Here, we show that upon calcium-induced junction biogenesis in Madin-Darby canine kidney cells, ABαC, a major protein phosphatase (PP)2A holoenzyme, is recruited...

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Bibliografiske detaljer
Main Authors: Nunbhakdi-Craig, Viyada, Machleidt, Thomas, Ogris, Egon, Bellotto, Dennis, White, Charles L., Sontag, Estelle
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173154/
https://ncbi.nlm.nih.gov/pubmed/12196510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200206114
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