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Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins
We utilize structurally targeted peptides to identify a “t(C) fusion switch” inherent to the coil domains of the neuronal t-SNARE that pairs with the cognate v-SNARE. The t(C) fusion switch is located in the membrane-proximal portion of the t-SNARE and controls the rate at which the helical bundle t...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173141/ https://ncbi.nlm.nih.gov/pubmed/12213837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200112081 |
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