cGMP-mediated signaling via cGKIα is required for the guidance and connectivity of sensory axons

Previous in vitro studies using cGMP or cAMP revealed a cross-talk between signaling mechanisms activated by axonal guidance receptors. However, the molecular elements modulated by cyclic nucleotides in growth cones are not well understood. cGMP is a second messenger with several distinct targets in...

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Autori principali: Schmidt, Hannes, Werner, Matthias, Heppenstall, Paul A., Henning, Mechthild, Moré, Margret I., Kühbandner, Susanne, Lewin, Gary R., Hofmann, Franz, Feil, Robert, Rathjen, Fritz G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173065/
https://ncbi.nlm.nih.gov/pubmed/12417579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200207058
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