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Tuberous sclerosis complex tumor suppressor–mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent

The evolution of mitogenic pathways has led to the parallel requirement for negative control mechanisms, which prevent aberrant growth and the development of cancer. Principally, such negative control mechanisms are represented by tumor suppressor genes, which normally act to constrain cell prolifer...

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Bibliografski detalji
Glavni autori: Jaeschke, Anja, Hartkamp, Joerg, Saitoh, Masao, Roworth, Wendy, Nobukuni, Takahiro, Hodges, Angela, Sampson, Julian, Thomas, George, Lamb, Richard
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173059/
https://ncbi.nlm.nih.gov/pubmed/12403809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.jcb.200206108
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