Tuberous sclerosis complex tumor suppressor–mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent

The evolution of mitogenic pathways has led to the parallel requirement for negative control mechanisms, which prevent aberrant growth and the development of cancer. Principally, such negative control mechanisms are represented by tumor suppressor genes, which normally act to constrain cell prolifer...

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Detalhes bibliográficos
Main Authors: Jaeschke, Anja, Hartkamp, Joerg, Saitoh, Masao, Roworth, Wendy, Nobukuni, Takahiro, Hodges, Angela, Sampson, Julian, Thomas, George, Lamb, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173059/
https://ncbi.nlm.nih.gov/pubmed/12403809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.jcb.200206108
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