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Down-regulation of Delta by proteolytic processing

Notch signaling regulates cell fate decisions during development through local cell interactions. Signaling is triggered by the interaction of the Notch receptor with its transmembrane ligands expressed on adjacent cells. Recent studies suggest that Delta is cleaved to release an extracellular fragm...

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Detalhes bibliográficos
Main Authors: Mishra-Gorur, Ketu, Rand, Matthew D., Perez-Villamil, Beatriz, Artavanis-Tsakonas, Spyros
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173041/
https://ncbi.nlm.nih.gov/pubmed/12403816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200203117
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