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Down-regulation of Delta by proteolytic processing

Notch signaling regulates cell fate decisions during development through local cell interactions. Signaling is triggered by the interaction of the Notch receptor with its transmembrane ligands expressed on adjacent cells. Recent studies suggest that Delta is cleaved to release an extracellular fragm...

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Main Authors: Mishra-Gorur, Ketu, Rand, Matthew D., Perez-Villamil, Beatriz, Artavanis-Tsakonas, Spyros
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173041/
https://ncbi.nlm.nih.gov/pubmed/12403816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200203117
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