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Low density lipoprotein receptor–related protein is a calreticulin coreceptor that signals focal adhesion disassembly

Thrombospondin (TSP) signals focal adhesion disassembly (the intermediate adhesive state) through interactions with cell surface calreticulin (CRT). TSP or a peptide (hep I) of the active site induces focal adhesion disassembly through binding to CRT, which activates phosphoinositide 3-kinase (PI3K)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Orr, Anthony Wayne, Pedraza, Claudio E., Pallero, Manuel Antonio, Elzie, Carrie A., Goicoechea, Silvia, Strickland, Dudley K., Murphy-Ullrich, Joanne E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172996/
https://ncbi.nlm.nih.gov/pubmed/12821648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200302069
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