Low density lipoprotein receptor–related protein is a calreticulin coreceptor that signals focal adhesion disassembly

Thrombospondin (TSP) signals focal adhesion disassembly (the intermediate adhesive state) through interactions with cell surface calreticulin (CRT). TSP or a peptide (hep I) of the active site induces focal adhesion disassembly through binding to CRT, which activates phosphoinositide 3-kinase (PI3K)...

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Main Authors: Orr, Anthony Wayne, Pedraza, Claudio E., Pallero, Manuel Antonio, Elzie, Carrie A., Goicoechea, Silvia, Strickland, Dudley K., Murphy-Ullrich, Joanne E.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172996/
https://ncbi.nlm.nih.gov/pubmed/12821648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200302069
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