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Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation

Akey step in lipolytic activation of adipocytes is the translocation of hormone-sensitive lipase (HSL) from the cytosol to the surface of the lipid storage droplet. Adipocytes from perilipin-null animals have an elevated basal rate of lipolysis compared with adipocytes from wild-type mice, but fail...

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Detalles Bibliográficos
Main Authors: Sztalryd, Carole, Xu, Guoheng, Dorward, Heidi, Tansey, John T., Contreras, Juan A., Kimmel, Alan R., Londos, Constantine
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172984/
https://ncbi.nlm.nih.gov/pubmed/12810697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200210169
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