Activation of Hormone-sensitive Lipase Requires Two Steps, Protein Phosphorylation and Binding to the PAT-1 Domain of Lipid Droplet Coat Proteins

Lipolysis is an important metabolic pathway controlling energy homeostasis through degradation of triglycerides stored in lipid droplets and release of fatty acids. Lipid droplets of mammalian cells are coated with one or more members of the PAT protein family, which serve important functions in reg...

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Detalhes bibliográficos
Main Authors: Wang, Hong, Hu, Liping, Dalen, Knut, Dorward, Heidi, Marcinkiewicz, Amy, Russell, Deanna, Gong, Dawei, Londos, Constantine, Yamaguchi, Tomohiro, Holm, Cecilia, Rizzo, Mark A., Brasaemle, Dawn, Sztalryd, Carole
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797282/
https://ncbi.nlm.nih.gov/pubmed/19717842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006726
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