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Regulation of leading edge microtubule and actin dynamics downstream of Rac1
Actin in migrating cells is regulated by Rho GTPases. However, Rho proteins might also affect microtubules (MTs). Here, we used time-lapse microscopy of PtK1 cells to examine MT regulation downstream of Rac1. In these cells, “pioneer” MTs growing into leading-edge protrusions exhibited a decreased c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172968/ https://ncbi.nlm.nih.gov/pubmed/12796474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303082 |
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