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Identification of XMAP215 as a microtubule-destabilizing factor in Xenopus egg extract by biochemical purification
Microtubules (MTs) polymerized with GMPCPP, a slowly hydrolyzable GTP analogue, are stable in buffer but are rapidly depolymerized in Xenopus egg extracts. This depolymerization is independent of three previously identified MT destabilizers (Op18, katanin, and XKCM1/KinI). We purified the factor res...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172913/ https://ncbi.nlm.nih.gov/pubmed/12719474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200211095 |
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