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XMAP215–EB1 Interaction Is Required for Proper Spindle Assembly and Chromosome Segregation in Xenopus Egg Extract

In metaphase Xenopus egg extracts, global microtubule growth is mainly promoted by two unrelated microtubule stabilizers, end-binding protein 1 (EB1) and XMAP215. Here, we explore their role and potential redundancy in the regulation of spindle assembly and function. We find that at physiological ex...

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Detalhes bibliográficos
Main Authors: Kronja, Iva, Kruljac-Letunic, Anamarija, Caudron-Herger, Maïwen, Bieling, Peter, Karsenti, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688548/
https://ncbi.nlm.nih.gov/pubmed/19369422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-10-1051
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