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Type X collagen gene regulation by Runx2 contributes directly to its hypertrophic chondrocyte–specific expression in vivo

The α1(X) collagen gene (Col10a1) is the only known hypertrophic chondrocyte–specific molecular marker. Until recently, few transcriptional factors specifying its tissue-specific expression have been identified. We show here that a 4-kb murine Col10a1 promoter can drive β-galactosidase expression in...

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Detalhes bibliográficos
Main Authors: Zheng, Qiping, Zhou, Guang, Morello, Roy, Chen, Yuqing, Garcia-Rojas, Xavier, Lee, Brendan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172833/
https://ncbi.nlm.nih.gov/pubmed/12952936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200211089
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