TARGETING RUNX2 EXPRESSION IN HYPERTROPHIC CHONDROCYTES IMPAIRS ENDOCHONDRAL OSSIFICATION DURING EARLY SKELETAL DEVELOPMENT

Runx2 is a known master transcription factor for osteoblast differentiation, as well as an essential regulator for chondrocyte maturation. Recently, more and more data has shown that Runx2 regulates hypertrophic chondrocyte-specific type X collagen gene (Col10a1) expression in different species. How...

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Main Authors: Ding, Ming, Lu, Yaojuan, Abbassi, Sam, Li, Feifei, Li, Xin, Song, Yu, Geoffroy, Valérie, Im, Hee-Jeong, Zheng, Qiping
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359397/
https://ncbi.nlm.nih.gov/pubmed/22223437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24045
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