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HIV Gag mimics the Tsg101-recruiting activity of the human Hrs protein
The HIV-1 Gag protein recruits the cellular factor Tsg101 to facilitate the final stages of virus budding. A conserved P(S/T)AP tetrapeptide motif within Gag (the “late domain”) binds directly to the NH(2)-terminal ubiquitin E2 variant (UEV) domain of Tsg101. In the cell, Tsg101 is required for biog...
Gorde:
Egile Nagusiak: | , , , , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
The Rockefeller University Press
2003
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172688/ https://ncbi.nlm.nih.gov/pubmed/12900394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200302138 |
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