A biomimetic motility assay provides insight into the mechanism of actin-based motility

Abiomimetic motility assay is used to analyze the mechanism of force production by site-directed polymerization of actin. Polystyrene microspheres, functionalized in a controlled fashion by the N-WASP protein, the ubiquitous activator of Arp2/3 complex, undergo actin-based propulsion in a medium tha...

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Bibliographic Details
Main Authors: Wiesner, Sebastian, Helfer, Emmanuele, Didry, Dominique, Ducouret, Guylaine, Lafuma, Françoise, Carlier, Marie-France, Pantaloni, Dominique
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172664/
https://ncbi.nlm.nih.gov/pubmed/12551957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200207148
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