Palmitoylation supports assembly and function of integrin–tetraspanin complexes

As observed previously, tetraspanin palmitoylation promotes tetraspanin microdomain assembly. Here, we show that palmitoylated integrins (α3, α6, and β4 subunits) and tetraspanins (CD9, CD81, and CD63) coexist in substantially overlapping complexes. Removal of β4 palmitoylation sites markedly impair...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yang, Xiuwei, Kovalenko, Oleg V., Tang, Wei, Claas, Christoph, Stipp, Christopher S., Hemler, Martin E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2004
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172609/
https://ncbi.nlm.nih.gov/pubmed/15611341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404100
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