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Palmitoylation supports assembly and function of integrin–tetraspanin complexes

As observed previously, tetraspanin palmitoylation promotes tetraspanin microdomain assembly. Here, we show that palmitoylated integrins (α3, α6, and β4 subunits) and tetraspanins (CD9, CD81, and CD63) coexist in substantially overlapping complexes. Removal of β4 palmitoylation sites markedly impair...

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Bibliografische gegevens
Hoofdauteurs: Yang, Xiuwei, Kovalenko, Oleg V., Tang, Wei, Claas, Christoph, Stipp, Christopher S., Hemler, Martin E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172609/
https://ncbi.nlm.nih.gov/pubmed/15611341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404100
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