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Palmitoylation supports assembly and function of integrin–tetraspanin complexes

As observed previously, tetraspanin palmitoylation promotes tetraspanin microdomain assembly. Here, we show that palmitoylated integrins (α3, α6, and β4 subunits) and tetraspanins (CD9, CD81, and CD63) coexist in substantially overlapping complexes. Removal of β4 palmitoylation sites markedly impair...

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Detalhes bibliográficos
Main Authors: Yang, Xiuwei, Kovalenko, Oleg V., Tang, Wei, Claas, Christoph, Stipp, Christopher S., Hemler, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172609/
https://ncbi.nlm.nih.gov/pubmed/15611341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404100
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