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SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor–induced apoptosis at the plasma membrane

Fas (CD95, APO-1, TNFRSF6) is a TNF receptor superfamily member that directly triggers apoptosis and contributes to the maintenance of lymphocyte homeostasis and prevention of autoimmunity. Although FADD and caspase-8 have been identified as key intracellular mediators of Fas signaling, it is not cl...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Siegel, Richard M., Muppidi, Jagan R., Sarker, Malabika, Lobito, Adrian, Jen, Melinda, Martin, David, Straus, Stephen E., Lenardo, Michael J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Rockefeller University Press 2004
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172594/
https://ncbi.nlm.nih.gov/pubmed/15557123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200406101
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