Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP

As cancer cells traverse collagen-rich extracellular matrix (ECM) barriers and intravasate, they adopt a fibroblast-like phenotype and engage undefined proteolytic cascades that mediate invasive activity. Herein, we find that fibroblasts and cancer cells express an indistinguishable pericellular col...

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Detalhes bibliográficos
Main Authors: Sabeh, Farideh, Ota, Ichiro, Holmbeck, Kenn, Birkedal-Hansen, Henning, Soloway, Paul, Balbin, Milagros, Lopez-Otin, Carlos, Shapiro, Steven, Inada, Masaki, Krane, Stephen, Allen, Edward, Chung, Duane, Weiss, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172570/
https://ncbi.nlm.nih.gov/pubmed/15557125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200408028
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