The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone

In the lactating breast, ERBB4 localizes to the nuclei of secretory epithelium while regulating activities of the signal transducer and activator of transcription (STAT) 5A transcription factor essential for milk-gene expression. We have identified an intrinsic ERBB4 NLS (residues 676–684) within th...

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Bibliografiska uppgifter
Huvudupphovsmän: Williams, Christopher C., Allison, June G., Vidal, Gregory A., Burow, Matthew E., Beckman, Barbara S., Marrero, Luis, Jones, Frank E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2004
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172499/
https://ncbi.nlm.nih.gov/pubmed/15534001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200403155
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