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The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles

Although mitotic and meiotic spindles maintain a steady-state length during metaphase, their antiparallel microtubules slide toward spindle poles at a constant rate. This “poleward flux” of microtubules occurs in many organisms and may provide part of the force for chromosome segregation. We use qua...

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Main Authors: Miyamoto, David T., Perlman, Zachary E., Burbank, Kendra S., Groen, Aaron C., Mitchison, Timothy J.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172449/
https://ncbi.nlm.nih.gov/pubmed/15583027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200407126
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