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Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes

Ubiquitination directs the sorting of cell surface receptors and other integral membrane proteins into the multivesicular body (MVB) pathway. Cargo proteins are subsequently deubiquitinated before their enclosure within MVB vesicles. In Saccharomyces cerevisiae, Bro1 functions at a late step of MVB...

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Bibliographic Details
Main Authors: Luhtala, Natalie, Odorizzi, Greg
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172414/
https://ncbi.nlm.nih.gov/pubmed/15326198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200403139
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