Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis

Endosomal sorting complexes required for transport (ESCRT-0, -I, -II, -III) execute cargo sorting and intralumenal vesicle (ILV) formation during conversion of endosomes to multivesicular bodies (MVBs). The AAA-ATPase Vps4 regulates the ESCRT-III polymer to facilitate membrane remodeling and ILV sci...

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Pubblicato in:J Cell Biol
Autori principali: Tseng, Chun-Che, Dean, Shirley, Davies, Brian A., Azmi, Ishara F., Pashkova, Natalya, Payne, Johanna A., Staffenhagen, Jennifer, West, Matt, Piper, Robert C., Odorizzi, Greg, Katzmann, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240856/
https://ncbi.nlm.nih.gov/pubmed/34160559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202102070
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