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Dual mechanisms specify Doa4-mediated deubiquitination at multivesicular bodies
Doa4 is a ubiquitin-specific protease in Saccharomyces cerevisiae that deubiquitinates integral membrane proteins sorted into the lumenal vesicles of late-endosomal multivesicular bodies (MVBs). We show that the non-catalytic N terminus of Doa4 mediates its recruitment to endosomes through its assoc...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868904/ https://ncbi.nlm.nih.gov/pubmed/17446860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601692 |
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