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Integrin α(V)β(6)-mediated activation of latent TGF-β requires the latent TGF-β binding protein-1
Transforming growth factor-βs (TGF-β) are secreted as inactive complexes containing the TGF-β, the TGF-β propeptide, also called the latency-associated protein (LAP), and the latent TGF-β binding protein (LTBP). Extracellular activation of this complex is a critical but incompletely understood step...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172370/ https://ncbi.nlm.nih.gov/pubmed/15184403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200312172 |
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