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Atypical protein kinase C (PKCζ/λ) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways

Insulin stimulation of adipocytes resulted in the recruitment of atypical PKC (PKCζ/λ) to plasma membrane lipid raft microdomains. This redistribution of PKCζ/λ was prevented by Clostridium difficile toxin B and by cholesterol depletion, but was unaffected by inhibition of phosphatidylinositol (PI)...

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Bibliografske podrobnosti
Main Authors: Kanzaki, Makoto, Mora, Silvia, Hwang, Joseph B., Saltiel, Alan R., Pessin, Jeffrey E.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172328/
https://ncbi.nlm.nih.gov/pubmed/14734537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200306152
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