Vav GEFs are required for β(2) integrin-dependent functions of neutrophils

Integrin regulation of neutrophils is essential for appropriate adhesion and transmigration into tissues. Vav proteins are Rho family guanine nucleotide exchange factors that become tyrosine phosphorylated in response to adhesion. Using Vav1/Vav3-deficient neutrophils (Vav1/3(ko)), we show that Vav...

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Detalhes bibliográficos
Main Authors: Gakidis, M. Angelica Martinez, Cullere, Xavier, Olson, Timothy, Wilsbacher, Julie L., Zhang, Bin, Moores, Sheri L., Ley, Klaus, Swat, Wojciech, Mayadas, Tanya, Brugge, Joan S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172310/
https://ncbi.nlm.nih.gov/pubmed/15249579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404166
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