Vav GEFs are required for β(2) integrin-dependent functions of neutrophils

Integrin regulation of neutrophils is essential for appropriate adhesion and transmigration into tissues. Vav proteins are Rho family guanine nucleotide exchange factors that become tyrosine phosphorylated in response to adhesion. Using Vav1/Vav3-deficient neutrophils (Vav1/3(ko)), we show that Vav...

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Bibliografske podrobnosti
Main Authors: Gakidis, M. Angelica Martinez, Cullere, Xavier, Olson, Timothy, Wilsbacher, Julie L., Zhang, Bin, Moores, Sheri L., Ley, Klaus, Swat, Wojciech, Mayadas, Tanya, Brugge, Joan S.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2004
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172310/
https://ncbi.nlm.nih.gov/pubmed/15249579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200404166
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