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Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades
Mitogen-activated protein kinase (MAPK) cascades can operate as bistable switches residing in either of two different stable states. MAPK cascades are often embedded in positive feedback loops, which are considered to be a prerequisite for bistable behavior. Here we demonstrate that in the absence o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172246/ https://ncbi.nlm.nih.gov/pubmed/14744999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200308060 |
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