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A role for myosin-1A in the localization of a brush border disaccharidase
To gain insight regarding myosin-1A (M1A) function, we expressed a dominant negative fragment of this motor in the intestinal epithelial cell line, CACO-2(BBE). Sucrase isomaltase (SI), a transmembrane disaccharidase found in microvillar lipid rafts, was missing from the brush border (BB) in cells e...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172191/ https://ncbi.nlm.nih.gov/pubmed/15138292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200310031 |
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