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A role for myosin-1A in the localization of a brush border disaccharidase

To gain insight regarding myosin-1A (M1A) function, we expressed a dominant negative fragment of this motor in the intestinal epithelial cell line, CACO-2(BBE). Sucrase isomaltase (SI), a transmembrane disaccharidase found in microvillar lipid rafts, was missing from the brush border (BB) in cells e...

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Autors principals: Tyska, Matthew J., Mooseker, Mark S.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172191/
https://ncbi.nlm.nih.gov/pubmed/15138292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200310031
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