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p107 regulates neural precursor cells in the mammalian brain
Here we show a novel function for Retinoblastoma family member, p107 in controlling stem cell expansion in the mammalian brain. Adult p107-null mice had elevated numbers of proliferating progenitor cells in their lateral ventricles. In vitro neurosphere assays revealed striking increases in the numb...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172121/ https://ncbi.nlm.nih.gov/pubmed/15353549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200403156 |
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