Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization

Cytoplasmic linker protein (CLIP)-170, CLIP-115, and the dynactin subunit p150(Glued) are structurally related proteins, which associate specifically with the ends of growing microtubules (MTs). Here, we show that down-regulation of CLIP-170 by RNA interference results in a strongly reduced accumula...

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Detalhes bibliográficos
Main Authors: Lansbergen, Gideon, Komarova, Yulia, Modesti, Mauro, Wyman, Claire, Hoogenraad, Casper C., Goodson, Holly V., Lemaitre, Régis P., Drechsel, David N., van Munster, Erik, Gadella, Theodorus W.J., Grosveld, Frank, Galjart, Niels, Borisy, Gary G., Akhmanova, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172020/
https://ncbi.nlm.nih.gov/pubmed/15381688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200402082
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