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The mechanism of spindle assembly: functions of Ran and its target TPX2

Recent work has provided new insights into the mechanism of spindle assembly. Growing evidence supports a model in which the small GTPase Ran plays a central role in this process. Here, we examine the evidence for the existence of a RanGTP gradient around mitotic chromosomes and some controversial d...

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Autors principals: Gruss, Oliver J., Vernos, Isabelle
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172015/
https://ncbi.nlm.nih.gov/pubmed/15452138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200312112
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