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PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins

Integral peroxisomal membrane proteins (PMPs) are synthesized in the cytoplasm and imported posttranslationally. Here, we demonstrate that PEX19 binds and stabilizes newly synthesized PMPs in the cytosol, binds to multiple PMP targeting signals (mPTSs), interacts with the hydrophobic domains of PMP...

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Bibliografiske detaljer
Main Authors: Jones, Jacob M., Morrell, James C., Gould, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171958/
https://ncbi.nlm.nih.gov/pubmed/14709540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304111
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