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PEX19 is a predominantly cytosolic chaperone and import receptor for class 1 peroxisomal membrane proteins
Integral peroxisomal membrane proteins (PMPs) are synthesized in the cytoplasm and imported posttranslationally. Here, we demonstrate that PEX19 binds and stabilizes newly synthesized PMPs in the cytosol, binds to multiple PMP targeting signals (mPTSs), interacts with the hydrophobic domains of PMP...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171958/ https://ncbi.nlm.nih.gov/pubmed/14709540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304111 |
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