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The yeast S phase checkpoint enables replicating chromosomes to bi-orient and restrain spindle extension during S phase distress

The budding yeast S phase checkpoint responds to hydroxyurea-induced nucleotide depletion by preventing replication fork collapse and the segregation of unreplicated chromosomes. Although the block to chromosome segregation has been thought to occur by inhibiting anaphase, we show checkpoint-defecti...

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Hlavní autoři: Bachant, Jeff, Jessen, Shannon R., Kavanaugh, Sarah E., Fielding, Candida S.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171834/
https://ncbi.nlm.nih.gov/pubmed/15795314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412076
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