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The yeast S phase checkpoint enables replicating chromosomes to bi-orient and restrain spindle extension during S phase distress

The budding yeast S phase checkpoint responds to hydroxyurea-induced nucleotide depletion by preventing replication fork collapse and the segregation of unreplicated chromosomes. Although the block to chromosome segregation has been thought to occur by inhibiting anaphase, we show checkpoint-defecti...

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書誌詳細
主要な著者: Bachant, Jeff, Jessen, Shannon R., Kavanaugh, Sarah E., Fielding, Candida S.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171834/
https://ncbi.nlm.nih.gov/pubmed/15795314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412076
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