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A small surface hydrophobic stripe in the coiled-coil domain of type I keratins mediates tetramer stability

Intermediate filaments (IFs) are fibrous polymers encoded by a large family of differentially expressed genes that provide crucial structural support in the cytoplasm and nucleus in higher eukaryotes. The mechanisms involved in bringing together ∼16 elongated coiled-coil dimers to form an IF are poo...

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Autors principals: Bernot, Kelsie M., Lee, Chang-Hun, Coulombe, Pierre A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171788/
https://ncbi.nlm.nih.gov/pubmed/15767464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200408116
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