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Coiled-Coil Trigger Motifs in the 1B and 2B Rod Domain Segments Are Required for the Stability of Keratin Intermediate Filaments

Many α-helical proteins that form two-chain coiled coils possess a 13-residue trigger motif that seems to be required for the stability of the coiled coil. However, as currently defined, the motif is absent from intermediate filament (IF) protein chains, which nevertheless form segmented two-chain c...

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Detalhes bibliográficos
Main Authors: Wu, Kenneth C., Bryan, Janine T., Morasso, Maria I., Jang, Shyh-Ing, Lee, Jeung-Hoon, Yang, Jun-Mo, Marekov, Lyuben N., Parry, David A.D., Steinert, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15012/
https://ncbi.nlm.nih.gov/pubmed/11029054
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