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ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles
Rho-associated kinase (ROCK) I mediates signaling from Rho to the actin cytoskeleton. To investigate the in vivo functions of ROCK-I, we generated ROCK-I–deficient mice. Loss of ROCK-I resulted in failure of eyelid closure and closure of the ventral body wall, which gave rise to the eyes open at bir...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171774/ https://ncbi.nlm.nih.gov/pubmed/15753128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200411179 |
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