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Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain

Timely differentiation of progenitor cells is critical for development. In this study we asked whether global epigenetic mechanisms regulate timing of progenitor cell differentiation into myelin-forming oligodendrocytes in vivo. Histone deacetylation was essential during a specific temporal window o...

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Detalhes bibliográficos
Main Authors: Shen, Siming, Li, Jiadong, Casaccia-Bonnefil, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171688/
https://ncbi.nlm.nih.gov/pubmed/15897262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412101
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