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FIAT represses ATF4-mediated transcription to regulate bone mass in transgenic mice
We report the characterization of factor inhibiting activating transcription factor 4 (ATF4)–mediated transcription (FIAT), a leucine zipper nuclear protein. FIAT interacted with ATF4 to inhibit binding of ATF4 to DNA and block ATF4-mediated transcription of the osteocalcin gene in vitro. Transgenic...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171686/ https://ncbi.nlm.nih.gov/pubmed/15911876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412139 |
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