FIAT represses ATF4-mediated transcription to regulate bone mass in transgenic mice

We report the characterization of factor inhibiting activating transcription factor 4 (ATF4)–mediated transcription (FIAT), a leucine zipper nuclear protein. FIAT interacted with ATF4 to inhibit binding of ATF4 to DNA and block ATF4-mediated transcription of the osteocalcin gene in vitro. Transgenic...

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Detalhes bibliográficos
Main Authors: Yu, Vionnie W.C., Ambartsoumian, Gourgen, Verlinden, Lieve, Moir, Janet M., Prud'homme, Josée, Gauthier, Claude, Roughley, Peter J., St-Arnaud, René
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171686/
https://ncbi.nlm.nih.gov/pubmed/15911876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412139
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