The PSD95–nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death

The stress-activated protein kinase p38 and nitric oxide (NO) are proposed downstream effectors of excitotoxic cell death. Although the postsynaptic density protein PSD95 can recruit the calcium-dependent neuronal NO synthase (nNOS) to the mouth of the calcium-permeable NMDA receptor, and depletion...

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Bibliografiska uppgifter
Huvudupphovsmän: Cao, Jiong, Viholainen, Jenni I., Dart, Caroline, Warwick, Helen K., Leyland, Mark L., Courtney, Michael J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2005
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171658/
https://ncbi.nlm.nih.gov/pubmed/15631993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200407024
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