Effects of Arp2 and Arp3 nucleotide-binding pocket mutations on Arp2/3 complex function

Contributions of actin-related proteins (Arp) 2 and 3 nucleotide state to Arp2/3 complex function were tested using nucleotide-binding pocket (NBP) mutants in Saccharomyces cerevisiae. ATP binding by Arp2 and Arp3 was required for full Arp2/3 complex nucleation activity in vitro. Analysis of actin d...

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Autores principales: Martin, Adam C., Xu, Xiao-Ping, Rouiller, Isabelle, Kaksonen, Marko, Sun, Yidi, Belmont, Lisa, Volkmann, Niels, Hanein, Dorit, Welch, Matthew, Drubin, David G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2005
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171590/
https://ncbi.nlm.nih.gov/pubmed/15657399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200408177
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