Calreticulin signals upstream of calcineurin and MEF2C in a critical Ca(2+)-dependent signaling cascade

We uncovered a new pathway of interplay between calreticulin and myocyte-enhancer factor (MEF) 2C, a cardiac-specific transcription factor. We establish that calreticulin works upstream of calcineurin and MEF2C in a Ca(2+)-dependent signal transduction cascade that links the endoplasmic reticulum an...

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Detalhes bibliográficos
Main Authors: Lynch, Jeffrey, Guo, Lei, Gelebart, Pascal, Chilibeck, Kaari, Xu, Jian, Molkentin, Jeffery D., Agellon, Luis B., Michalak, Marek
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171392/
https://ncbi.nlm.nih.gov/pubmed/15998798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412156
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