Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A

Ubc13, a ubiquitin-conjugating enzyme (Ubc), requires the presence of a Ubc variant (Uev) for polyubiquitination. Uevs, although resembling Ubc in sequence and structure, lack the active site cysteine residue and are catalytically inactive. The yeast Uev (Mms2) incites noncanonical Lys63-linked poly...

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Detalhes bibliográficos
Main Authors: Andersen, Parker L., Zhou, Honglin, Pastushok, Landon, Moraes, Trevor, McKenna, Sean, Ziola, Barry, Ellison, Michael J., Dixit, Vishva M., Xiao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171356/
https://ncbi.nlm.nih.gov/pubmed/16129784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200502113
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