Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial–mesenchymal transition

The Akt family of kinases are activated by growth factors and regulate pleiotropic cellular activities. In this study, we provide evidence for isoform-specific positive and negative roles for Akt1 and -2 in regulating growth factor–stimulated phenotypes in breast epithelial cells. Insulin-like growt...

Full description

Saved in:
Bibliographic Details
Main Authors: Irie, Hanna Y., Pearline, Rachel V., Grueneberg, Dorre, Hsia, Maximilian, Ravichandran, Preethi, Kothari, Nayantara, Natesan, Sridaran, Brugge, Joan S.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2005
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171329/
https://ncbi.nlm.nih.gov/pubmed/16365168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200505087
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items