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MELAS: a new disease associated mitochondrial DNA mutation and evidence for further genetic heterogeneity

OBJECTIVES—To define the molecular genetic basis of the MELAS phenotype in five patients without any known mutation of mitochondrial DNA.
METHODS—Systematic automated mitochondrial DNA sequencing of all mitochondrial transfer RNA and cytochrome c oxidase genes was undertaken in five patients who had...

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Detalhes bibliográficos
Main Authors: Hanna, M, Nelson, I, Morgan-Hughes, J, Wood, N
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170312/
https://ncbi.nlm.nih.gov/pubmed/9771776
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