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Major decrease in the volume of the entorhinal cortex in patients with Alzheimer's disease carrying the apolipoprotein E ε4 allele

OBJECTIVE—Recent evidence indicates that the apolipoprotein E (ApoE) ε4 allele is a risk factor for developing Alzheimer's disease. It has also been proposed that it is associated with increased counts of amyloid plaques and neurofibrillary tangles that in turn are neuropathological hallmarks i...

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Detalhes bibliográficos
Main Authors: Juottonen, K, Lehtovirta, M, Helisalmi, S, Sr, P, Soininen, H
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170244/
https://ncbi.nlm.nih.gov/pubmed/9728943
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