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Major decrease in the volume of the entorhinal cortex in patients with Alzheimer's disease carrying the apolipoprotein E ε4 allele

OBJECTIVE—Recent evidence indicates that the apolipoprotein E (ApoE) ε4 allele is a risk factor for developing Alzheimer's disease. It has also been proposed that it is associated with increased counts of amyloid plaques and neurofibrillary tangles that in turn are neuropathological hallmarks i...

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Bibliografski detalji
Glavni autori: Juottonen, K, Lehtovirta, M, Helisalmi, S, Sr, P, Soininen, H
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 1998
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2170244/
https://ncbi.nlm.nih.gov/pubmed/9728943
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